Anti Soluble Fms-Like Tyrosine Kinase 1 (sFlt1)  Monoclonal Antibody
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Anti Soluble Fms-Like Tyrosine Kinase 1 (sFlt1) Monoclonal Antibody

A50572-100ug
Out of stock In stock
$699.00
$699.00

Anti Soluble Fms-Like Tyrosine Kinase 1 (sFlt1) Monoclonal Antibody

Anti Soluble Fms-Like Tyrosine Kinase 1 (sFlt1)  Monoclonal Antibody

Clone HI572    Catalog#: A50572

Description: Soluble Fms-like tyrosine kinase 1 (sFlt-1), also known as soluble vascular endothelial growth factor receptor 1 (sVEGFR-1), is a protein that plays a critical role in the regulation of angiogenesis, the process of forming new blood vessels from pre-existing vessels. It is a soluble form of the Flt-1 receptor, which is normally found on the surface of endothelial cells that line the interior surface of blood vessels. sFlt-1 functions by binding to vascular endothelial growth factors (VEGFs), which are molecules that promote the growth of new blood vessels. By sequestering VEGF, sFlt-1 prevents it from interacting with its cell surface receptor, thus inhibiting the signaling pathways that lead to angiogenesis. This mechanism is important in various physiological and pathological processes, including embryonic development, wound healing, and the growth of tumors.

Isotype:

Mouse IgG

Species reactivity:

Mouse

Production:

Tissue culture

Purification:

Protein A/G

Applications:

ELISA, WB, IFA, IHC, CLIA, LFA, IP

Immunogen: 

Recombinant sFlt1 Antigen

Storage: 

Store at +4°C short term (1-2 weeks). Store at -20°C long term.

Formulation:

PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug.

Clonality:

Monoclonal

 

Reference: 
1.Huber, N., Kollmann, T. M., & Schramek, D. (2018). Soluble Flt1: a multi-faceted player in health and disease. Journal of Molecular Medicine, 96(11), 1163-1175.
2. Wang, Y., Li, J., & Zhang, Y. (2020). The role of sFlt-1 in the pathogenesis of preeclampsia and other diseases. Frontiers in Cell and Developmental Biology, 8, 575.


Intended for research use only. Not for human, therapeutic, or diagnostic applications.


The buyer cannot sell or otherwise transfer this product for Commercial Purposes without written approval of Humimmu LLC.  
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