Anti-Human CD3E Monoclonal Antibody
Anti-Human CD3E Monoclonal Antibody
Clone OKT-3 Catalog#: AB5628
Description:
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
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Isotype: |
Mouse IgG2a(D134G)CH1+Human IgG1 CH2+CH3-Mouse kappa |
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Reactivities: |
Human |
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Clone: |
OKT-3 |
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Target: |
CD3E |
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Alternative Name: |
OKt3,OKT-3; CD3E; CD3 epsilon; T3E; TCRE;T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e; OKT3 |
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Expression System: |
CHO |
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Purity: |
>95% Determined by SDS-PAGE |
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Purification: |
Protein A |
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Sterility: |
0.2 μM filtered |
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Recommended Dilution Buffer: |
ABDB-1002 or PBS, pH 7.4,Contains no stabilizers or preservatives. |
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Immunogen: |
N/A |
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Storage: |
2 weeks, 2-8℃ under sterile conditions after reconstitution. Avoid repeated freeze-thaw. -80°C for a long-term storage. |
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Formulation: |
PBS, pH 7.4,Contains no stabilizers or preservatives |
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Endotoxin: |
<1EU/mg ,Determined by LAL gel clotting assay |
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Clonality: |
Monoclonal |
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Protocol Information: |
Since applications vary, each investigator should use the application references as a guide to help estimate the appropriate dose or concentration. The dose or concentration can be further optimized experimentally in a dose response or titration experiment. |
Intended for research use only. Not for human, therapeutic, or diagnostic applications.
The buyer cannot sell or otherwise transfer this product for Commercial Purposes without written approval of Humimmu LLC.
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