{"product_id":"anti-yersinia-pestis-v-antigen-y-pestis-v-monoclonal-antibody","title":"Anti-Yersinia pestis V antigen (Y. Pestis\/V) Monoclonal Antibody","description":"\u003cmeta charset=\"utf-8\"\u003e\n\u003cp align=\"center\"\u003e\u003cstrong\u003eAnti-Yersinia pestis V antigen (Y. Pestis\/V) Monoclonal Antibody\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e \u003cstrong\u003eClone HI356          Catalog#: A35006               Datasheet  \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDescription\u003c\/strong\u003e\u003cstrong\u003e:\u003c\/strong\u003e Yersinia pestis is a Gram negative bacterium listed as a category A infective agent that causes bubonic, septicemic, and pneumonic plague. The latter form is of special interest to biodefense, as it is highly lethal and transmitted through aerosol. The \u003cem data-mce-fragment=\"1\"\u003eY. pestis\u003c\/em\u003e virulence (V) antigen has been identified as a potent protective antigen (PA) against plague and has consequently been evaluated as a subunit vaccine candidate and as a target for passive immunotherapy. V antigen is required for translocation of bacterial effector proteins into host cells.\u003c\/p\u003e\n\u003ctable border=\"1\" cellspacing=\"0\" cellpadding=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd valign=\"top\"\u003e\n\u003cp\u003eIsotype:\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"top\" width=\"290\"\u003e\n\u003cp\u003eIgG\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"top\"\u003e\n\u003cp\u003eSpecies reactivity:\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"top\" width=\"290\"\u003e\n\u003cp\u003eMouse\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"top\"\u003e\n\u003cp\u003eProduction:\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"top\" width=\"290\"\u003e\n\u003cp\u003eTissue culture\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"top\"\u003e\n\u003cp\u003ePurification:\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"top\" width=\"290\"\u003e\n\u003cp\u003eProtein A\/G\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"top\"\u003e\n\u003cp\u003eApplications:\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"top\" width=\"290\"\u003e\n\u003cp\u003eNeutralization assay, ELISA, IFA, FACS\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"top\"\u003e\n\u003cp\u003eImmunogen: \u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"top\" width=\"290\"\u003e\n\u003cp\u003eRecombinant Yersinia pestis V antigen \u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"top\"\u003e\n\u003cp\u003eStorage: \u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"top\" width=\"290\"\u003e\n\u003cp\u003eStore at +4°C short term (1-2 weeks). Store at -20°C long term.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"top\"\u003e\n\u003cp\u003eFormulation:\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"top\" width=\"290\"\u003e\n\u003cp\u003ePBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU\/ug.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"top\"\u003e\n\u003cp\u003eClonality:\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"top\" width=\"290\"\u003e\n\u003cp\u003eMonoclonal\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReference:\u003cspan data-mce-fragment=\"1\"\u003e \u003c\/span\u003e \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1. He Anderson GW Jr, Worsham PL, et al. (1997). Protection of mice from fatal bubonic and pneumonic plague by passiveimmunization with monoclonal antibodies against the F1 protein of Yersinia pestis. Am J Trop Med Hyg. 56(4):471-473.\u003c\/p\u003e\n\u003cp\u003e2. Hill J, Leary SE, et al. (1997). Regions of Yersinia pestis V antigen that contribute to protection against plague identified by passive and active immunization. Infect Immun. 65(11): 4476-4482.\u003c\/p\u003e\n\u003cp\u003e3. Liu W, Ren J, et al.(2017). Identification and characterization of a neutralizing monoclonal antibody that provides complete protection against Yersinia pestis. PLoS One.12(5): e0177012.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePublications citing Humimmu products:   \u003c\/strong\u003e\u003c\/p\u003e\n\u003cspan id=\"ginger-button-for-rephrase\" title=\"Rephrase\" style=\"left: 276px; top: 442px; position: fixed; z-index: 51; visibility: visible;\"\u003e\u003c\/span\u003e","brand":"Humimmu","offers":[{"title":"100μg","offer_id":47153795498279,"sku":"A35006-100ug","price":699.0,"currency_code":"USD","in_stock":true},{"title":"500μg","offer_id":47153795531047,"sku":"A35006-500ug","price":1999.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":47153795563815,"sku":"A35006-1mg","price":2999.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0735\/6481\/5655\/files\/AntiY.PestisVMonoclonalAntibody.jpg?v=1700380124","url":"https:\/\/www.humimmu.com\/products\/anti-yersinia-pestis-v-antigen-y-pestis-v-monoclonal-antibody","provider":"Humimmu","version":"1.0","type":"link"}