Anti Human Neurofilament Light chain (hNfL) Monoclonal Antibody
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Anti Human Neurofilament Light chain (hNfL) Monoclonal Antibody

A50566-100ug
Out of stock In stock
$699.00
$699.00

Anti Human Neurofilament Light chain (hNfL) Monoclonal Antibody

Clone HI566                               Catalog#: A50566

Description: The human neurofilament light chain (NfL) is a type of intermediate filament protein that is specifically found in the nervous system. It is one of the three subunits that make up the neurofilament proteins, which are the most abundant proteins in the axons of neurons. The other two subunits are the medium (NfM) and heavy (NfH) chains. Neurofilaments provide structural support to the axons, helping to maintain their diameter and resist mechanical stress. They also play a role in the spatial organization of the axonal cytoskeleton and are involved in regulating axonal transport. The light chain, in particular, is thought to be involved in the assembly and stabilization of the neurofilament network.

Isotype:

Mouse IgG

Species reactivity:

Mouse

Production:

Tissue culture

Purification:

Protein A/G

Applications:

ELISA, WB, IFA, IHC, CLIA, LFA, IP

Immunogen: 

Recombinant human NfL protein 

Storage: 

Store at +4°C short term (1-2 weeks). Store at -20°C long term.

Formulation:

PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug.

Clonality:

Monoclonal

 

Reference: 
1. Miller, R. J., & Johnson, G. V. (2002). Axonal transport and Alzheimer's disease: the good, the bad, and the uncertain. Journal of Neurochemistry, 83(3), 701-707.
2. Petzold, A., & Tumani, H. (2012). Neurofilament light chain as a blood and CSF biomarker for neurodegenerative diseases. Journal of Neurology, 259(1), 5-14.
3. Zetterberg, H., & Blennow, K. (2019). Fluid biomarkers of neurodegeneration in Alzheimer's 

Intended for research use only. Not for human, therapeutic, or diagnostic applications.
The buyer cannot sell or otherwise transfer this product for Commercial Purposes without written approval of Humimmu LLC.  
Copyright 2024. Humimmu LLC.  All Rights Reserved

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