Anti-Human Nectin-4 Monoclonal Antibody
Anti-Human Nectin-4 Monoclonal Antibody
Clone: Enfbio Catalog#: AB5306
Description:
Nectin-4 (Nectin cell adhesion molecule 4) is a member of the Nectin and Necdin-like families of cell adhesion molecules. It is highly expressed in normal embryonic and fetal tissues but not in adult healthy tissues. Nectin-4 is a type I transmembrane protein, and the extracellular region of the dimeric Nectin-4 consists of three Ig domains: Ig V-type and Ig C-type. Metalloproteinase TACE / ADAM-17 can degrade the extracellular domain, resulting in the production of soluble Nectin-4. This secreted form has been found in patients with breast cancer.
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Reactivities: |
Human |
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Target: |
Nectin-4 |
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Clone: |
Enfbio |
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Isotype: |
Human IgG1(K214R)-kappa |
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Alternative Name: |
Anti-human Nectin-4; Anti-human cell adhesion molecule nectin-4 |
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Recommend Isotype Controls: |
Anti-HEL Human IgG1 (K214R)-Kappa Isotype control |
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Recommended Dilution Buffer: |
ABDB-1002 or PBS, pH 7.4,Contains no stabilizers or preservatives. |
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Immunogen: |
N/A |
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Formulation: |
PBS, pH 7.4,Contains no stabilizers or preservatives |
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Endotoxin: |
<1EU/mg ,Determined by LAL gel clotting assay |
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Purity: |
>95% Determined by SDS-PAGE |
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Sterility: |
0.2 μM filtered |
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Expression System: |
CHO |
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Purification: |
Protein A |
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Clonality: |
Monoclonal |
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Storage: |
2 weeks, 2-8°C under sterile conditions after reconstitution. Avoid repeated freeze-thaw. -80°C for a long-term storage. |
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Protocol Information: |
Since applications vary, each investigator should use the application references as a guide to help estimate the appropriate dose or concentration. The dose or concentration can be further optimized experimentally in a dose response or titration experiment. |
Intended for research use only. Not for human, therapeutic, or diagnostic applications.
The buyer cannot sell or otherwise transfer this product for Commercial Purposes without written approval of Humimmu LLC.
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