Anti-Human TMPRSS6 Monoclonal Antibody, clone: exerenibart, Ships in 3-5 Weeks
Anti-Human TMPRSS6 Monoclonal Antibody, clone: exerenibart
Clone: exerenibart Catalog#: N25024
Description:
Exerenibart is a IgG4 kappa monoclonal antibody that targets TMPRSS6. TMPRSS6 (transmembrane serine protease 6, also known as matriptase-2) is a type II transmembrane serine protease with important biological functions, particularly in regulating iron homeostasis. TMPRSS6 also participates in the regulation of the ferritin iron transporter axis, affecting iron uptake and distribution. The functional abnormalities of TMPRSS6 are associated with various iron metabolism disorders, making it a potential target for research and treatment of iron metabolism disorders.
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Reactivities: |
Human |
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Target: |
TMPRSS6 |
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Clone: |
exerenibart |
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Isotype: |
immunoglobulin G4-kappa |
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Alternative Name: |
transmembrane serine protease 6, matriptase-2, MT2 |
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Recommended Dilution Buffer: |
PBS, pH 7.4,Contains no stabilizers or preservatives. |
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Immunogen: |
N/A |
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Formulation: |
PBS, pH 7.4,Contains no stabilizers or preservatives |
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Endotoxin: |
<1EU/mg ,Determined by LAL gel clotting assay |
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Purity: |
>95% Determined by SDS-PAGE |
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Sterility: |
0.2 μM filtered |
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Purification: |
Protein A |
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Clonality: |
Monoclonal |
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Storage: |
2 weeks, 2-8°C under sterile conditions after reconstitution. Avoid repeated freeze-thaw. -80°C for a long-term storage. |
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Protocol Information: |
Since applications vary, each investigator should use the application references as a guide to help estimate the appropriate dose or concentration. The dose or concentration can be further optimized experimentally in a dose response or titration experiment. |
Intended for research use only. Not for human, therapeutic, or diagnostic applications.
The buyer cannot sell or otherwise transfer this product for Commercial Purposes without written approval of Humimmu LLC.
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