Anti-Human IL-31RA Monoclonal Antibody
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Anti-Human IL-31RA Monoclonal Antibody

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Anti-Human IL-31RA Monoclonal Antibody

Clone: Nembio                            Catalog#: AB5311


IL-31 is a tetrahelical cytokine discovered by Dillon et al. in 2004, which belongs to the IL-6 cytokine family but has lower homology with IL-6 cytokine family. It is mainly secreted by activated CD4+ T lymphocytes, especially activated Th2 cells, mast cells, monocytes/macrophages, and dendritic cells. In addition to IL-6 and IL-31, this family also includes IL-11, IL-27, oncostatin, leukemia inhibitory factor, ciliary neurotrophic factor, and cardiotrophin-like factor. The main target sites of IL-31 are the skin, lungs, intestines, and nervous system. IL-31 also has low expression levels in testes, bone marrow, thymus, spleen, kidneys, and skeletal muscles. Studies have shown that IL-31 plays an important role in allergic diseases such as dermatitis, itching, and allergic asthma.








Human IgG2(C130S/R132K/E136G/S137G/C218S/H263Q/R350Q/Q414E/G441DEL/K442DEL)-kappa

Alternative Name:

CIM 331,CIM331;interleukin 31 receptor subunit alpha, interleukin 31 receptor A

Recommend Isotype Controls:


Recommended Dilution Buffer:

ABDB-1002 or PBS, pH 7.4,Contains no stabilizers or preservatives.




PBS, pH 7.4,Contains no stabilizers or preservatives


<1EU/mg ,Determined by LAL gel clotting assay


>95% Determined by SDS-PAGE


0.2 μM filtered

Expression System:



Protein A




2 weeks, 2-8°C under sterile conditions after reconstitution. Avoid repeated freeze-thaw. -80°C for a long-term storage.

Protocol Information:

Since applications vary, each investigator should use the application references as a guide to help estimate the appropriate dose or concentration. The dose or concentration can be further optimized experimentally in a dose response or titration experiment.


Intended for research use only. Not for human, therapeutic, or diagnostic applications.

The buyer cannot sell or otherwise transfer this product for Commercial Purposes without written approval of Humimmu LLC.  

Copyright 2023. Humimmu LLC.  All Rights Reserved

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