Anti-Human IL-17A Monoclonal Antibody
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Anti-Human IL-17A Monoclonal Antibody

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Anti-Human IL-17A Monoclonal Antibody

Clone: Ixebio                      Catalog#: AB5829


Interleukin-17A (IL-17A), commonly known as IL-17, was first discovered at the transcriptional level through a mouse T cell hybridoma. Several years later, researchers found that IL-17A is expressed in CD4+ T cells and can induce IL-6 in fibroblasts. Subsequently, more studies revealed that IL-17A is a major mediator of T cell communication with the hematopoietic system and overexpression in vivo leads to extramedullary granulopoiesis. In the 21st century, significant progress has been made in understanding IL-17A. Research has shown that Th17 cell lineage commitment is independent of traditional activation pathways such as STAT4 and STAT6, meaning that IL-17A and other inflammatory factors like IL-6 are not identical. IL-17A plays a key role in host defense against various microbial pathogens and tissue inflammation, making it an important target for drug discovery in treating various forms of autoimmune and inflammatory diseases.








Human IgG4(S228P)-kappa

Alternative Name:

LY2439821;CTLA8; CTLA-8; CTLA8cytotoxic T-lymphocyte-associated serine esterase 8; Cytotoxic T-lymphocyte-associated antigen 8; IL17; IL-17; IL17A; IL-17A; IL-17Acytotoxic T-lymphocyte-associated protein 8; IL-17CTLA-8; IL17interleukin-17A; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17A

Recommend Isotype Controls:

Anti-HEL Human IgG4(S228P)-Kappa Isotype control

Recommended Dilution Buffer:

ABDB-1002 or PBS, pH 7.4,Contains no stabilizers or preservatives.




PBS, pH 7.4,Contains no stabilizers or preservatives


<1EU/mg ,Determined by LAL gel clotting assay


>95% Determined by SDS-PAGE


0.2 μM filtered

Expression System:



Protein A




2 weeks, 2-8°C under sterile conditions after reconstitution. Avoid repeated freeze-thaw. -80°C for a long-term storage.

Protocol Information:

Since applications vary, each investigator should use the application references as a guide to help estimate the appropriate dose or concentration. The dose or concentration can be further optimized experimentally in a dose response or titration experiment.


Intended for research use only. Not for human, therapeutic, or diagnostic applications.

The buyer cannot sell or otherwise transfer this product for Commercial Purposes without written approval of Humimmu LLC.  

Copyright 2023. Humimmu LLC.  All Rights Reserved

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