Anti-Human IGF1R Monoclonal Antibody
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Anti-Human IGF1R Monoclonal Antibody

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Anti-Human IGF1R Monoclonal Antibody

Clone: Robbio                              Catalog#: AB5845


The Insulin-like growth factor (IGF) system comprises two main receptors, IGF-IR and IGF-IIR. Both IGF-IR and IGF-IIR are transmembrane glycoproteins that differ completely in their structure and function. IGF-IR is a tetramer of two equal α-subunits and two equal β-subunits. Structurally, IGF-IR resembles the insulin receptor with 60% homology. Deregulation of IGF-IR signalling has been reported to contribute to a variety of diseases including diabetic retinopathy, diabetic nephropathy, age-related macular degeneration, cardiovascular disease, and aging and in a variety of cancers.








Human IgG1(E356D/M358L)-kappa

Alternative Name:

19D12,SCH 717454,SCH717454;insulin-like growth factor 1 receptor, IGF1-R, IGF-1R, CD221

Recommend Isotype Controls:

Anti-HEL Human IgG1(E356D/M358L)-Kappa Isotype control

Recommended Dilution Buffer:

ABDB-1002 or PBS, pH 7.4,Contains no stabilizers or preservatives.




PBS, pH 7.4,Contains no stabilizers or preservatives


<1EU/mg ,Determined by LAL gel clotting assay


>95% Determined by SDS-PAGE


0.2 μM filtered

Expression System:



Protein A




2 weeks, 2-8°C under sterile conditions after reconstitution. Avoid repeated freeze-thaw. -80°C for a long-term storage.

Protocol Information:

Since applications vary, each investigator should use the application references as a guide to help estimate the appropriate dose or concentration. The dose or concentration can be further optimized experimentally in a dose response or titration experiment.


Intended for research use only. Not for human, therapeutic, or diagnostic applications.

The buyer cannot sell or otherwise transfer this product for Commercial Purposes without written approval of Humimmu LLC.  

Copyright 2024. Humimmu LLC.  All Rights Reserved

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