Anti-Human CD257 Monoclonal Antibody
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Anti-Human CD257 Monoclonal Antibody

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Anti-Human CD257 Monoclonal Antibody

Clone Tabbio                          Catalog#: AB5851


CD257, also known as BAFF, is a crucial B cell survival factor and a member of the tumor necrosis factor (TNF) ligand family. It exists in two forms: soluble and membrane-bound. BAFF is expressed on various cell types, including monocytes, dendritic cells, and bone marrow stromal cells. There are three receptors for BAFF: TNFRSF13B/TACI (transmembrane activator and calcium modulator and cyclophilin ligand interactor), TNFRSF17/BCMA (B cell maturation antigen), and TNFRSF13C/BAFFR (B cell activation factor receptor). BAFF plays a key role in supporting B cell survival and proliferation, regulating class switching recombination, and selecting autoimmune B cells by binding to its receptors. In addition, some studies have found that BAFF can also promote T cell activation, proliferation, and differentiation.








Human IgG4(S228P)-kappa(S70N)

Alternative Name:

LY2127399;tumor necrosis factor (TNF) superfamily member 13B, BAFF, THANK, TALL1, TALL-1, BLYS, BLyS, B cell activating factor, B lymphocyte activator,TNFSF13B

Recommend Isotype Controls:


Recommended Dilution Buffer:

ABDB-1002 or PBS, pH 7.4,Contains no stabilizers or preservatives.




PBS, pH 7.4,Contains no stabilizers or preservatives


<1EU/mg ,Determined by LAL gel clotting assay


>95% Determined by SDS-PAGE


0.2 μM filtered

Expression System:



Protein A




2 weeks, 2-8°C under sterile conditions after reconstitution. Avoid repeated freeze-thaw. -80°C for a long-term storage.

Protocol Information:

Since applications vary, each investigator should use the application references as a guide to help estimate the appropriate dose or concentration. The dose or concentration can be further optimized experimentally in a dose response or titration experiment.

Intended for research use only. Not for human, therapeutic, or diagnostic applications.

The buyer cannot sell or otherwise transfer this product for Commercial Purposes without written approval of Humimmu LLC.  

Copyright 2024. Humimmu LLC.  All Rights Reserved

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