Anti Nipah Virus NP (NiV-NP) Monoclonal Antibody
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Anti Nipah Virus NP (NiV-NP) Monoclonal Antibody

A50403-100ug
Out of stock In stock
$699.00
$699.00

Anti Nipah Virus NP (NiV-NP) Monoclonal Antibody

 

Clone HI403                             Catalog#: A50403


Description: Nipah virus (NiV) belongs to the Paramyxoviridae family and Henipavirus genus. It is considered a zoonotic disease that can cause encephalitis, pneumonia, and vasculitis in humans after being transmitted from bats. NiV infects humans through bats and contaminated intermediate hosts such as pigs. Currently, there is no effective vaccine or therapeutic drug for NiV. The NiV genome is a negative-stranded single-stranded RNA with a size of approximately 18.2kb. It is similar to other paramyxoviruses and belongs to the enveloped virus group. Two major glycoproteins on the surface of the virus particle, G and F, are responsible for binding to the host cell receptors ephrin-B2 and ephrin-B3, completing the adsorption process. The nucleocapsid protein NP is a large structural protein in the viral particle and can be used as a target for clinical diagnosis.

Isotype:

Mouse IgG2a

Species reactivity:

Mouse

Production:

Tissue culture

Purification:

Protein A/G

Applications:

ELISA, WB, IFA, IHC, CLIA, LFA, IP

Immunogen: 

E.Coli express recombinant human Nipah virus NP protein

Storage: 

Store at +4°C short term (1-2 weeks). Store at -20°C long term.

Formulation:

PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug.

Clonality:

Monoclonal

References

1.Devnath P, Wajed S, et al. (2022). The pathogenesis of Nipah virus: A review. Microb Pathog.Sep;170:105693.

2.Alam AM.(2022). Nipah virus, an emerging zoonotic disease causing fatal encephalitis. Clin Med (Lond)Jul:22(4):348-352.

3.Monath TP, Nichols R,et al.(2022). Recombinant vesicular stomatitis vaccine against Nipah virus has a favorable safety profile: Model for assessment of livevaccines with neurotropic potential. PLoS Pathog.Jun 27:18(6):e1010658.

Intended for research use only. Not for human, therapeutic, or diagnostic applications.
The buyer cannot sell or otherwise transfer this product for Commercial Purposes without written approval of Humimmu LLC.
Copyright 2023. Humimmu LLC. All Rights Reserved

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