Anti-Human F11 Monoclonal Antibody, Clone: adimanebart
Clone: amrecibart Catalog#: N25005
Description:
Amrecibart is a IgG4 kappa monoclonal antibody that targets human F11. F11, also known as coagulation factor XI, is a key protein in the coagulation cascade. The F11 gene encodes coagulation factor XI, which circulates in the blood in an inactive form. Once activated, it promotes clot formation and stabilization, thereby enabling effective hemostasis. Its biological significance lies in maintaining normal blood coagulation balance and preventing bleeding disorders. Deficiencies or defects in F11 may lead to hereditary factor XI deficiency.
Reactivities: |
Human |
Target: |
F11 |
Clone: |
amrecibart |
Isotype: |
immunoglobulin G4-kappa |
Alternative Name: |
FXI, plasma thromboplastin antecedent, PTA |
Recommended Dilution Buffer: |
PBS, pH 7.4,Contains no stabilizers or preservatives. |
Immunogen: |
N/A |
Formulation: |
PBS, pH 7.4,Contains no stabilizers or preservatives |
Endotoxin: |
<1EU/mg ,Determined by LAL gel clotting assay |
Purity: |
>95% Determined by SDS-PAGE |
Sterility: |
0.2 μM filtered |
Purification: |
Protein A |
Clonality: |
Monoclonal |
Storage: |
2 weeks, 2-8°C under sterile conditions after reconstitution. Avoid repeated freeze-thaw. -80°C for a long-term storage. |
Protocol Information: |
Since applications vary, each investigator should use the application references as a guide to help estimate the appropriate dose or concentration. The dose or concentration can be further optimized experimentally in a dose response or titration experiment. |
Intended for research use only. Not for human, therapeutic, or diagnostic applications.
The buyer cannot sell or otherwise transfer this product for Commercial Purposes without written approval of Humimmu LLC.
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